When someone has a specific type of anemia caused by low vitamin B12, getting B12 shots can make their darkened skin and nails, and early gray hair, go back to normal.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

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Reversible hyperpigmentation of skin and nails with white hair due to vitamin B12 deficiency.

Case Report

Human

1986 Aug

A person with a specific type of anemia caused by low B12 had dark skin, dark nails, and gray hair — after getting B12 shots, all those changes went away. The study shows the treatment fixed the problem, just like the claim says.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Reversible hyperpigmentation of skin and nails with white hair due to vitamin B12 deficiency.

Score: 20

DOI: 10.1001/ARCHDERM.1986.01660200068018

Similar Assertions

A person with a vitamin B12 deficiency had their skin and nails turn darker and their hair turn gray too early, but after getting a B12 shot, all of those changes went back to normal.

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96%

If your hair is turning gray because you don’t have enough vitamin B12, fixing that deficiency might bring back your natural hair color—but this hardly ever happens, and it won’t work if something else is causing the graying.

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76%