Adults with type 2 diabetes who did aerobic exercise had about 27 less ng/mL of ICAM-1 (an inflammation marker) than those who didn't exercise, after 12 weeks.
Scientific Claim
Aerobic exercise was associated with a 27.1 ng/mL greater reduction in ICAM-1 levels compared to no structured exercise in adults with type 2 diabetes and BMI ≥23 kg/m² after 12 weeks.
Original Statement
“ICAM-1 Group A: 163.5 (2.89) to 136.2 (2.41); Group 2: 181.6 (2.92) to 181.4 (3.10). Within-group change for Group A: Z = -3.89, p < 0.001; Group 2: Z = -0.28, p = 0.778. Overall change comparison: F = 19.72, p < 0.001.”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study design is quasi-experimental, which can only show association, not causation. The claim uses 'associated with' correctly.
Evidence from Studies
Supporting (1)
Comparison of the Effect of Aerobic Exercise Versus Yoga on Endothelial Function and Insulin Resistance in Type 2 Diabetic Patients