correlational
Analysis v1
32
0
After one night without sleep, healthy men show changes in two blood chemicals related to blood vessel health, suggesting their blood vessels might not work as well.
Scientific Claim
In 40 healthy men aged 31.2±6.3 years with BMI 24.6±2.6 kg/m², 24 hours of sleep deprivation is associated with a 9.4 unit decrease in L-arginine levels and a 0.1 unit increase in asymmetric dimethylarginine levels, which are biomarkers of endothelial function.
Original Statement
“L-Arg and ADMA levels changed from 78.2±12.9 and 0.3±0.1 at baseline to 68.8±10.2 and 0.4±0.1 after 24-hr SD, respectively (p=0.001, p=0.004).”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study design supports correlational claims about biomarker changes without implying causation. The language correctly avoids causal terms.
Evidence from Studies
Supporting (1)
32
Contradicting (0)
0
No contradicting evidence found