mechanistic
Analysis v1
Strong Support
Almost all basal cell skin cancers have a damaged version of the TP53 gene — a gene that normally stops cells from turning cancerous — and the damage looks like it was caused by sunburns.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
1
Ultraviolet Radiation and Basal Cell Carcinoma: An Environmental Perspective
Narrative Review
2021This study says sun exposure causes skin cancer by damaging DNA, and that matches the claim that sun damage leads to specific gene mutations in skin cancer — so yes, it supports the claim.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.