Botox injections make wrinkles look better for the first few years, but after 15 years, everyone’s wrinkles look about the same no matter how often or how young they started getting injections.

Evidence from Studies

Supporting (1)

Community contributions welcome

A 15-Year Computational Twin Modeling Study of Botulinum Toxin A Frequency and Age-Related Facial Aging.

Computational/Algorithm Study

2025 Dec 4

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

A 15-Year Computational Twin Modeling Study of Botulinum Toxin A Frequency and Age-Related Facial Aging.

DOI: 10.1007/s00266-025-05497-1

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No matter when or how often you get Botox, your skin keeps getting thinner over time, and Botox doesn’t slow that down.

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How often you get Botox or how young you start doesn’t change how your face ages naturally — your skin follows the same aging path no matter what.

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