Cells with MOTS-c used less oxygen, but adding folic acid brought oxygen use back to normal.

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The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

Randomized Controlled Trial

Animal & In Vitro

2015 Mar 3

Source Study

The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

Score: 13

DOI: 10.1016/j.cmet.2015.02.009

Similar Assertions

When scientists added MOTS-c to cells in a dish, the cells started using more sugar for energy and turned on a key energy sensor called AMPK—until they added folic acid or blocked AMPK, which stopped the effect.

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