Cells with MOTS-c used less oxygen, but adding folic acid brought oxygen use back to normal.

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Evidence from Studies

Supporting (0)

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No supporting evidence found

Contradicting (1)

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The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

Randomized Controlled Trial

Animal

2015 Mar 3

The study says MOTS-c affects metabolism by interfering with a vitamin B9 pathway, but it never tested oxygen use in these specific cells or checked if adding folic acid fixes it.

Source Study

The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

Score: 13

DOI: 10.1016/j.cmet.2015.02.009

Similar Assertions

When scientists added MOTS-c to cells in a dish, the cells started using more sugar for energy and turned on a key energy sensor called AMPK—until they added folic acid or blocked AMPK, which stopped the effect.

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