Taking creatine for a week may lower protein breakdown in young men by about 7.5%, but it doesn’t seem to have the same effect in young women.

47

Pro

0

Against

Evidence from Studies

Supporting (1)

47

Community contributions welcome

47

Effects of acute creatine monohydrate supplementation on leucine kinetics and mixed-muscle protein synthesis.

Randomized Controlled Trial

Human

2001 Sep

The study gave people creatine pills the same way the claim says, and found that in men, their bodies broke down less protein — but not in women — which is exactly what the claim says.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Effects of acute creatine monohydrate supplementation on leucine kinetics and mixed-muscle protein synthesis.

Score: 47

DOI: 10.1152/jappl.2001.91.3.1041

Similar Assertions

Taking creatine for a week may help men’s bodies use less of a key protein building block during workouts, but it doesn’t seem to do the same for women—so the effect might be different by sex.

47

0

90%

Taking creatine for a week like this doesn’t make you weigh more or gain more muscle in young, healthy men and women.

47

0

83%

Taking creatine powder for about a week—first a lot, then a little—can boost the amount of creatine in your muscles by over 13%, which helps your muscles store more energy.

47

0

82%

Taking creatine for a week doesn’t make your muscles start building protein faster, even if you take a lot of it at first and then less later.

47

0

80%

Taking 21 grams of creatine a day for 5 days can boost the amount of creatine in your muscles by about 30%, but it doesn’t make your muscles build protein faster or break it down slower, whether you’ve eaten or not.

30

0

76%