Some new treatments for thyroid eye disease might work better by hitting two different pathways in the eye that cause swelling, instead of just one.

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Evidence from Studies

Supporting (1)

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Targeting TSH and IGF-1 Receptors to Treat Thyroid Eye Disease

Narrative Review

2020 Dec

The study says that drugs targeting the TSH receptor could block two problem pathways in eye disease, not just one, which matches the claim.

Contradicting (0)

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Targeting TSH and IGF-1 Receptors to Treat Thyroid Eye Disease

Score: 1

DOI: 10.1159/000511538

Similar Assertions

Using two treatments together—one for the TSH receptor and one for the IGF-1 receptor—might work better and cause fewer side effects for people with thyroid eye disease than using just one of them alone.

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When a certain receptor in eye cells gets turned on, it triggers processes that cause the cells to release a gooey substance, leading to eye bulging and swelling in people with thyroid eye disease.

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A drug called teprotumumab helps people with thyroid eye disease by reducing swelling, pain, and other symptoms — and it's already approved by health regulators.

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