Eating earlier in the day for 4 days didn't change levels of two growth-related hormones in the evening for overweight people compared to eating throughout the day.
Scientific Claim
Early time-restricted feeding did not significantly affect evening levels of IGF-binding protein 3 (IGFBP-3) or human growth hormone (HGH) in overweight adults after 4 days of intervention compared to a control schedule.
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
definitive
Can make definitive causal claims
Assessment Explanation
This is a randomized controlled trial with direct measurements of hormone levels. The verb 'did not significantly affect' is appropriate for this null finding.
Source Excerpt
“Apparent decreases in evening levels of IGF-1 and IGFBP-1 did not reach statistical significance (both p = 0.11), while IGFBP-3 and HGH levels were unchanged (p ≥ 0.25).”
Evidence from Studies
Supporting Evidence (1)
The study measured IGFBP-3 and HGH levels in the evening and found no statistically significant differences between eTRF and control conditions (p ≥ 0.25).
Early Time-Restricted Feeding Improves 24-Hour Glucose Levels and Affects Markers of the Circadian Clock, Aging, and Autophagy in Humans