Eating earlier in the day for 4 days slightly increased both 'bad' and 'good' cholesterol levels in the morning for overweight people compared to eating throughout the day.
Scientific Claim
Early time-restricted feeding increased morning LDL cholesterol by 9 mg/dl and HDL cholesterol by 3 mg/dl in overweight adults after 4 days of intervention compared to a control schedule.
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
definitive
Can make definitive causal claims
Assessment Explanation
This is a randomized controlled trial with direct measurements of cholesterol levels. The verb 'increased' is appropriate for these specific short-term effects.
Source Excerpt
“In the morning, eTRF increased LDL and HDL cholesterol by 9 ± 4 mg/dl (p = 0.02) and 3 ± 1 mg/dl (p = 0.03), respectively, but did not affect levels of triglycerides (p = 0.29) or free fatty acids (p = 0.73).”
Evidence from Studies
Supporting Evidence (1)
The study measured cholesterol levels in the morning and found statistically significant increases in both LDL and HDL cholesterol with eTRF. The effect direction is neutral as both types of cholesterol increased, which may not be clinically significant.
Early Time-Restricted Feeding Improves 24-Hour Glucose Levels and Affects Markers of the Circadian Clock, Aging, and Autophagy in Humans