Eating early in the day lowers two key hormones (leptin and GLP-1) in the morning, which may reflect the body’s natural rhythm adjusting to food timing.
Scientific Claim
Early time-restricted feeding decreases morning levels of leptin by 4 ± 1 ng/mL and GLP-1 by 0.8 ± 0.3 pmol/mL in overweight adults, suggesting a circadian modulation of satiety hormones.
Original Statement
“eTRF decreased morning levels of active ghrelin (Δ=−43±15 pg/ml; p=0.009), leptin (Δ=−4±1 ng/ml; p=0.01) and GLP-1 (Δ=−0.8±0.3 pmol/ml; p=0.008) but did not affect PYY (p=0.25).”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
definitive
Can make definitive causal claims
Assessment Explanation
The RCT design with direct hormone measurement supports definitive causal claims. The effect sizes and p-values are reported with precision.
Evidence from Studies
Supporting (0)
Contradicting (1)
Early Time-Restricted Feeding Reduces Appetite and Increases Fat Oxidation but Does Not Affect Energy Expenditure in Humans
The study looked at how eating earlier affects hunger and fat burning, but it didn’t measure the two hormones (leptin and GLP-1) that the claim says drop — so we can’t say if the claim is right or wrong.