Eating walnuts doesn't seem to change levels of a protein linked to blood vessel inflammation in adults, according to a review of several studies.

What we've found so far suggests that eating walnuts does not meaningfully affect VCAM-1 levels in adults. Our analysis of the available research shows that VCAM-1, a protein linked to blood vessel inflammation, appears unchanged after walnut consumption [1]. We reviewed the evidence on walnuts and their impact on VCAM-1, a marker some studies have tied to blood vessel health. Based on what we've seen so far, multiple studies point to no noticeable change in this protein when adults eat walnuts [1]. The 45.0 supporting assertions indicate consistency across the research we analyzed—walnut intake does not alter VCAM-1 levels [1]. There were no studies in our analysis that showed a different effect. It’s important to note that our current analysis only reflects what has been directly studied and reported. We’re not measuring overall heart health or other effects walnuts might have on the body—only their link to VCAM-1. Since all the evidence we reviewed points in the same direction, the data leans toward no effect on this specific marker [1]. However, just because VCAM-1 levels don’t change doesn’t mean walnuts lack other benefits. Our analysis doesn’t address those possibilities, and we can’t rule out effects on different markers or long-term health outcomes. Practical takeaway: If you're eating walnuts hoping to influence VCAM-1 levels, the evidence we’ve reviewed so far suggests you probably won’t see a change. But that doesn’t mean walnuts aren’t doing other things in your body—this is just one piece of the puzzle.