descriptive
Analysis v1
Strong Support
Even in skin that looks perfectly healthy, some cells already have the same DNA mutations found in skin cancers—but they’re rare and don’t cause cancer yet.
34
0
Evidence from Studies
Supporting (1)
34
Community contributions welcome
34
UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes in human skin
Cross-Sectional Study
Human
2021 JanEven in skin that never saw the sun, healthy people’s skin cells already have tiny DNA mistakes that can lead to cancer — and these mistakes build up as we age, even without sun exposure.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.