Taking creatine supplements doesn’t change the acidity inside your muscle cells or the MRI signal from your muscles, even though other tests show something different.

44

Pro

0

Against

Evidence from Studies

Supporting (1)

44

Community contributions welcome

44

Changes in Human Muscle Transverse Relaxation Following Short‐Term Creatine Supplementation

Randomized Controlled Trial

Human

2002 May

The study gave people creatine pills and checked their muscles with two different tools: one that measures water in cells (MRI) and one that measures chemicals (spectroscopy). The MRI showed no change in water or acidity, but the chemical test did show changes — just like the claim said.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Changes in Human Muscle Transverse Relaxation Following Short‐Term Creatine Supplementation

Score: 44

DOI: 10.1113/eph8702382

Similar Assertions

Some people who take creatine monohydrate supplements see a small increase in water inside their muscle cells, which shows up as a change in a special MRI scan — but only if their body actually responds to creatine.

44

0

77%