When male rats are stressed out for a month by being stuck in small tubes, their pancreas cells become super sensitive to sugar and pump out way more insulin than normal when tested in a dish.

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Evidence from Studies

Supporting (1)

11

Community contributions welcome

11

Effect of chronic psychological stress on insulin release from rat isolated pancreatic islets.

Cohort Study

Animal

2006 May 30

The study found that rats stressed for 30 days had pancreas cells that released more insulin when exposed to high sugar in a dish, even though their bodies showed less insulin in the blood — meaning their pancreas cells were actually working better, not worse.

Contradicting (0)

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Effect of chronic psychological stress on insulin release from rat isolated pancreatic islets.

Score: 11

DOI: 10.1016/J.LFS.2005.12.032

Similar Assertions

When male rats are stressed by being stuck in a small space for an hour, twice a day, for two weeks or a month, their bodies produce less insulin—even though their blood sugar goes up. This suggests their pancreas isn’t releasing insulin properly.

11

0

89%

Stressing out male lab rats for a long time makes their bodies worse at handling sugar, even though their resting blood sugar stays the same.

16

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80%