mechanistic
Analysis v1
Strong Support
Even when the brain's main body clock loses its rhythm, the thyroid gland in mice can still keep its own daily rhythm going — suggesting it doesn’t completely depend on signals from the brain’s clock center.
10
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Evidence from Studies
Supporting (1)
10
Community contributions welcome
10
The Circadian Clock Is Sustained in the Thyroid Gland of VIP Receptor 2 Deficient Mice
Cohort Study
Animal
2021The study shows that even when a key brain signal (VIP/VPAC2) is broken, the thyroid’s daily rhythm still keeps ticking, just a bit off schedule — which means it doesn’t rely entirely on the brain’s main clock.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.