Even when mice can't use the usual testosterone signal in their liver, testosterone still lowers a protein called hepcidin—suggesting it’s using a different trick, maybe by boosting red blood cell production, to do this.

13

Pro

0

Against

Evidence from Studies

Supporting (1)

13

Community contributions welcome

13

Hepcidin is not essential for mediating testosterone's effects on erythropoiesis

Randomized Controlled Trial

Animal

2020 Jan

Even when the liver’s testosterone sensor (androgen receptor) is broken, testosterone still boosts red blood cell production — suggesting it works through a different, hidden pathway that also lowers hepcidin, a protein that blocks iron use.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Hepcidin is not essential for mediating testosterone's effects on erythropoiesis

Score: 13

DOI: 10.1111/andr.12622

Similar Assertions

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