For HIV patients with belly fat who responded to tesamorelin, denser subcutaneous fat (on CT scans) was linked to less subcutaneous fat area, showing that fat quality and quantity are related.

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Evidence from Studies

Supporting (1)

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Tesamorelin improves fat quality independent of changes in fat quantity

Randomized Controlled Trial

Human

The study found that when people with HIV took tesamorelin, their belly fat became denser and healthier, even if the total amount of fat didn’t change — meaning denser fat equals less fatty, better-quality fat.

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No contradicting evidence found

Source Study

Tesamorelin improves fat quality independent of changes in fat quantity

Score: 66

DOI: 10.1097/qad.0000000000002897

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