In untrained young adults, performing standing calf raises with the knee straight leads to significantly greater muscle growth in the calf muscles compared to seated calf raises with the knee bent,...
Mechanism
Synthesis from 1 study
When the calf muscle is stretched while pushing up, it pulls harder on itself and builds up more waste, which tells the muscle to grow bigger. This only happens strongly when the knee is straight, not bent.
Most probable mechanism
When the calf muscle is stretched while contracting, it pulls harder on its fibers and builds up more waste products, which signals the muscle to grow bigger. This happens more when the knee is straight than when it's bent.
Knee extension during plantarflexion elongates the gastrocnemius muscle, increasing passive tension and sarcomere strain across its fibers
Increased sarcomere strain activates mechanotransduction pathways involving integrins, focal adhesion kinase, and mTOR signaling in muscle cells
Greater muscle lengthening during contraction elevates metabolic stress through localized hypoxia and lactate accumulation, disrupting cellular homeostasis
Mechanical tension and metabolic stress trigger upregulation of anabolic signaling molecules, including IGF-1, and activate satellite cells to contribute nuclei to muscle fibers
Muscle protein synthesis exceeds degradation, resulting in net accretion of contractile proteins and increased muscle fiber cross-sectional area
Evidence from Studies
Supporting (1)
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Triceps surae muscle hypertrophy is greater after standing versus seated calf-raise training
Contradicting (0)
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Gold Standard Evidence Needed
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