Strong Support
quantitative
Analysis v3
History

In people who regularly lift weights, training the side shoulder muscle with dumbbells or cables for 8 weeks results in the same small to moderate increase in muscle thickness, regardless of whether...

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0
Against

Mechanism

Synthesis from 1 study

How it works

The side shoulder muscle grows the same amount whether the weight feels heavier at the start or the end of the movement, because the full stretch and pull over the same motion is enough to make the muscle build more protein. The total tension matters more than when it peaks.

Most probable mechanism

In Simple Terms

When the side shoulder muscle is stretched and contracted through the same range of motion, the force applied to the muscle fibers activates signals that tell the muscle to build more protein, leading to thicker fibers. This happens whether the resistance is heavier at the start or at the end of the movement, because the total amount of stretch and tension over the full motion is enough to trigger growth.

Causal chain
1

The lateral deltoid muscle is stretched to a length where it enters the descending limb of the length-tension relationship during shoulder abduction.

Supported by evidence
which leads to
2

Mechanical tension applied to the muscle fibers during contraction activates intracellular signaling pathways, including mTOR and MAPK, which increase the rate of muscle protein synthesis.

Indirect evidence only
which leads to
3

Muscle protein synthesis exceeds proteolytic breakdown, resulting in net accumulation of myofibrillar proteins within muscle fibers.

Verified by multiple studies
which leads to
4

The accumulation of myofibrillar proteins increases muscle fiber cross-sectional area, which is measured as increased muscle thickness.

Verified by multiple studies

Evidence from Studies

Supporting (1)

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Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

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