For people with HIV taking tesamorelin, changes in their growth hormone levels didn't match changes in their trunk muscle thickness or size.

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The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area in Adults with HIV

Randomized Controlled Trial

Human

2019

The study found that a drug called tesamorelin made HIV patients' trunk muscles bigger and denser, and since this drug is known to increase a hormone called IGF-1, it suggests that IGF-1 changes are linked to muscle improvements — the opposite of what the claim says.

Source Study

The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area in Adults with HIV

Score: 60

DOI: 10.14283/jfa.2018.45

Similar Assertions

Changes in a growth hormone-related factor didn't match changes in muscle density or size in people with HIV and belly fat taking tesamorelin.

93%

In people with HIV and belly fat who responded to tesamorelin, muscle density changes were linked to belly fat loss but not to changes in a growth-related hormone.

88%

Tesamorelin boosts a key growth hormone-related protein in HIV patients without affecting their blood sugar levels.

86%

Rising IGF-1 levels helped explain some of the muscle growth from the drug, but not all of it—so other factors are also at work.

85%

People with HIV who have belly fat and are on medication to control the virus who took tesamorelin had higher levels of a growth-related hormone called IGF-1. This finding is from the abstract summary - full study details were not available

85%