Even if your body releases a lot of muscle-building hormones after a workout, that doesn’t mean you’ll grow more muscle than someone whose hormone levels don’t spike as much—both people end up getting just as strong and muscular.

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Evidence from Studies

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Load-induced human skeletal muscle hypertrophy: Mechanisms, myths, and misconceptions

Narrative Review

2025 Nov 21

This study says that even if your body releases a lot of muscle-building hormones after a workout, it doesn’t actually make your muscles grow bigger—what matters is how hard you lift, not how much hormone you produce.

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Load-induced human skeletal muscle hypertrophy: Mechanisms, myths, and misconceptions

Score: 1

DOI: 10.1016/j.jshs.2025.101104

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