Getting cholesterol extremely low doesn’t seem to make people more likely to get cancer, stroke, diabetes, liver problems, muscle issues, or cataracts — at least not in the time frame studied.

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Evidence from Studies

Supporting (1)

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Safety and efficacy of very low LDL-cholesterol intensive lowering: a meta-analysis and meta-regression of randomized trials.

Systematic Review With Meta-Analysis

Human

2023 Feb 2

This big study looked at thousands of people with very low cholesterol and found they didn’t have more problems like cancer, strokes, or diabetes than people with higher cholesterol—so having very low cholesterol isn’t dangerous for these conditions.

Contradicting (0)

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No contradicting evidence found

Source Study

Safety and efficacy of very low LDL-cholesterol intensive lowering: a meta-analysis and meta-regression of randomized trials.

Score: 59

DOI: 10.1093/ehjcvp/pvac049

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