Goldenseal, a plant-based supplement, may help lower 'bad' cholesterol in animals and lab tests by telling the liver to pull more cholesterol out of the blood.

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Evidence from Studies

Supporting (1)

6

Community contributions welcome

6

The medicinal plant goldenseal is a natural LDL-lowering agent with multiple bioactive components and new action mechanisms Published, JLR Papers in Press, August 2, 2006.

Cohort Study

Animal

2006 Oct

Scientists found that goldenseal, a plant used in medicine, lowers bad cholesterol in lab cells and hamsters by helping the liver remove more cholesterol from the blood. This matches what the claim says.

Contradicting (0)

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Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

The medicinal plant goldenseal is a natural LDL-lowering agent with multiple bioactive components and new action mechanisms Published, JLR Papers in Press, August 2, 2006.

Score: 6

DOI: 10.1194/jlr.M600195-JLR200

Similar Assertions

A natural herb called goldenseal might help lower bad cholesterol more effectively than a similar compound called berberine, by helping the liver remove more cholesterol from the blood — based on tests in human liver cells and hamsters.

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82%

Goldenseal, a herbal supplement, has some mysterious chemicals (besides berberine) that help your liver pull more bad cholesterol out of your blood—making it even better at lowering cholesterol than berberine by itself.

6

0

72%