Having a tough childhood doesn’t seem to leave a detectable mark on DNA or RNA damage in the blood of new moms, even when accounting for other health factors.

Scientific Claim

Childhood maltreatment is not associated with altered levels of serum 8-OH(d)G, a biomarker of oxidative DNA and RNA damage, in postpartum women after controlling for age, smoking, BMI, and other confounders.

Original Statement

“The analyses of serum and plasma oxidative stress biomarkers assessed in study cohort II revealed... no significant association between maltreatment load and the serum levels of 8-OH(d)G (b = 0.0155, p = 0.19).”

From study:The Association of Childhood Maltreatment With Lipid Peroxidation and DNA Damage in Postpartum Women

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

association

Can only show association/correlation

Assessment Explanation

The claim correctly uses 'not associated with' and references the specific biomarker and population. The p-value and confounder control are accurately reflected.

Evidence from Studies

Supporting (1)

The Association of Childhood Maltreatment With Lipid Peroxidation and DNA Damage in Postpartum Women

Cross-Sectional Study

Human

Contradicting (0)

No contradicting evidence found

Source Study

The Association of Childhood Maltreatment With Lipid Peroxidation and DNA Damage in Postpartum Women

Score: 45

DOI: 10.3389/fpsyt.2019.00023

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