In adult rats, how well their muscles use essential amino acids to build protein depends on whether they get their protein spread out through the day or all at once, and also on how much leucine is in the food they eat.

9

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Evidence from Studies

Supporting (1)

9

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9

Leucine Guides Meal Distribution of Dietary Protein for Muscle Protein Synthesis and Mass

Cohort Study

Animal

The study found that when rats got their protein spread evenly across meals and from sources high in leucine (like whey), their muscles grew better — proving that both when and what kind of protein they ate mattered.

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Source Study

Leucine Guides Meal Distribution of Dietary Protein for Muscle Protein Synthesis and Mass

Score: 9

DOI: 10.1096/fasebj.29.1_supplement.129.3

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