mechanistic
Analysis v1
Strong Support
In some animals that are genetically prone to it, a 'leaky gut' might come before type 1 diabetes and help trigger it by letting gut bacteria sneak into the body and turn on the immune system near the pancreas.
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Evidence from Studies
Supporting (1)
1
Community contributions welcome
1
Leaky Gut As a Danger Signal for Autoimmune Diseases
Narrative Review
Animal
2017The study explains that a leaky gut can let bad stuff into the body that might turn on the immune system in people who are genetically prone to autoimmune diseases, which matches the main idea of the claim.
Contradicting (0)
0
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No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.