When animals eat a lot of sugar like fructose, especially along with high blood sugar, their liver makes more of a substance called lactate. This could sometimes build up and cause a problem called lactate acidosis, especially in people with diabetes or liver issues.

When animals eat fructose, their liver breaks it down super fast without needing insulin, turning it mostly into glucose and lactate — and this might mess with the liver's energy and lead to health problems if it happens too much.

Eating too much fructose—like the sugar in soda and candy—can slow down your liver’s ability to burn fat, making fat build up and mess up your metabolism.

Eating a lot of fructose (like in sugary drinks) might turn up the activity of certain liver enzymes that process sugar and make fat, especially in people who already have metabolic problems like obesity or diabetes.

Eating too much fructose—like the sugar in soda and sweetened snacks—may slow down your liver’s ability to burn fat, which can lead to fat buildup and make your body less responsive to insulin.

Eating fructose (like in sugary drinks) might be worse for your body than eating glucose (like in bread), because it can lead to more harmful fat buildup, insulin problems, and higher uric acid — all of which could increase your risk of heart disease.