In obese people with low growth hormone taking tesamorelin, higher IGF-I levels are linked to better mitochondrial energy efficiency, measured by τPCr.

When obese people with low growth hormone took a drug called tesamorelin for a year, their muscle energy recovery got better, which means their muscle cells may have become better at making energy.

In obese people with low growth hormone taking tesamorelin, the link between higher IGF-I and better muscle energy recovery is even stronger than in the whole group of participants.

Taking tesamorelin for a year makes IGF-I levels rise much more in obese people with low growth hormone than taking a dummy pill, with a clear difference between the two groups.

Taking tesamorelin for a year makes the hormone IGF-I go up much more in obese people with low growth hormone compared to taking a sugar pill.

In obese people with low growth hormone taking tesamorelin, the link between higher IGF-I and better muscle energy recovery is even stronger than in the whole study group.