In people with high triglycerides, a low-fat high-carb diet changes where the fat in their blood comes from — but scientists still can't explain where about 1 in 5 of those fat molecules are coming from.

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Pro

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Against

Evidence from Studies

Supporting (1)

31

Community contributions welcome

31

Effects of a low-fat, high-carbohydrate diet on VLDL-triglyceride assembly, production, and clearance.

Cross-Sectional Study

Human

1999 Oct

This study found that in people with high triglycerides, eating a low-fat, high-carb diet makes their body use less fat from the blood to make VLDL triglycerides, and there’s still some missing fat that can’t be explained — just like the claim says.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Effects of a low-fat, high-carbohydrate diet on VLDL-triglyceride assembly, production, and clearance.

Score: 31

DOI: 10.1172/JCI6572

Similar Assertions

People with high triglycerides process fat differently than those with normal levels when eating a low-fat, high-carb diet — their bodies use different fat sources and clear fat slower, which may explain why this diet raises their triglycerides more than it does in others.

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83%

Eating a diet low in fat and high in carbs makes the body less able to clear fat from the blood, causing triglyceride levels to rise sharply.

31

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77%