In people with obesity, fat tissue that makes more estrogen seems to be linked to having more total body fat.

28

Pro

0

Against

Evidence from Studies

Supporting (1)

28

Community contributions welcome

28

Intra‐adipose sex steroid metabolism and body fat distribution in idiopathic human obesity

Cross-Sectional Study

Human

2007 Mar

The study found that people with more body fat had higher levels of a specific enzyme (aromatase) in their fat tissue, which makes estrogen — and this matches the claim that more fat means more of this enzyme, possibly helping explain why fat builds up.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Intra‐adipose sex steroid metabolism and body fat distribution in idiopathic human obesity

Score: 28

DOI: 10.1111/j.1365-2265.2007.02755.x

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