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Strong Opposition
correlational
Analysis v3
History

Large DNA deletions in skin that never gets sunburned are linked to past sun exposure—likely because UV light breaks DNA strands, and the cell’s repair job often messes up, deleting big chunks.

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Against

Evidence from Studies

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Contradicting (1)

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UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes in human skin

Cross-Sectional Study
Human & In Vitro
2021 Jan

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Source Study

UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes in human skin

Score: 34
DOI: 10.1371/journal.pgen.1009302

Similar Assertions

Even skin that never gets direct sunlight still shows DNA damage from past sun exposure, and this damage doesn’t get worse as people get older—it just stays the same.

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75%

After you get sunburned, your skin temporarily stops making tan pigment because a protein called ATM redirects another protein (MITF) to fix DNA damage instead of making color.

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72%