Mice eating a fatty diet have more of the stress hormone in their fur, suggesting their bodies are under more prolonged stress over time.
Scientific Claim
Female ICR mice on a high-fat diet (60% kcal from fat) for four weeks show significantly higher hair corticosterone levels than controls, indicating elevated long-term glucocorticoid exposure.
Original Statement
“Hair corticosterone was higher in HF mice than in CON (P<0.05).”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study measures a biomarker but does not confirm stress via challenge tests. 'Higher levels' is appropriate as it reflects association, not causation or stress diagnosis.
Evidence from Studies
Supporting (1)
The study found that female mice eating a very fatty diet for four weeks had more stress hormone in their hair than mice eating a normal diet, meaning they were under more long-term stress.