mechanistic
Analysis v1
Strong Support
Mice given a certain hormone and baking soda don't get high blood pressure from too much salt because their cells swap potassium for sodium to stay hydrated — but mice given regular salt don't do this and their cells dry out.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
9
Deoxycorticosterone-acetate salt-sensitive hypertension initiates with intracellular K+ and water loss
Cross-Sectional Study
Animal
Mice given DOCA and baking soda (NaHCO₃) keep their blood pressure normal because they swap lost potassium for sodium inside cells, preventing cell dehydration. Mice given DOCA and table salt (NaCl) don’t do this right away, so their cells dry out and blood pressure rises.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
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