correlational
Analysis v1
Strong Support
In mice, taking a very high dose of statins might make them swim longer and act less helpless, which could mean it helps with depression-like behavior—even though it also seems to affect their movement in other ways.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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Adverse neurobehavioral changes with reduced blood and brain cholinesterase activities in mice treated with statins
Cross-Sectional Study
Animal
2024 JanThe study gave mice high doses of statins and found they swam longer and gave up less easily, which can look like an antidepressant effect, even though their movement was slowed in other activities.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.