mechanistic
Analysis v1
Strong Support

In people with celiac disease, a bacterial enzyme called microbial transglutaminase might glue together the tiny seals between gut cells, making the gut leakier and letting more of the harmful wheat protein (gliadin) slip through, which could make symptoms worse.

1
Pro
0
Against

Evidence from Studies

Supporting (1)

1

Community contributions welcome

This study says that a food additive called microbial transglutaminase can make the gut lining leakier in people with celiac disease, letting harmful wheat proteins slip through more easily—which is exactly what the claim says.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.