Training muscles while they are stretched leads to more muscle growth in muscles that cross two joints, like the calf's gastrocnemius, but does not lead to more growth in muscles that cross one...
Mechanism
Synthesis from 1 study
Muscles that stretch across two joints grow bigger when trained with the joint fully extended because they get pulled tighter and work harder under strain. Muscles that only cross one joint don't get stretched as much in this position, so they grow the same no matter how the joint is positioned.
Most probable mechanism
When a muscle that crosses two joints is stretched while contracting, its fibers experience more tension and damage, which triggers signals that build more muscle tissue. Muscles that cross only one joint don't stretch as much during this movement, so they don't grow as much from the same exercise.
Knee extension during plantarflexion places the gastrocnemius at a longer muscle length, increasing passive tension and stretching sarcomeres beyond their optimal overlap
Increased sarcomere strain activates mechanosensitive pathways including integrin, FAK, and mTOR signaling in muscle fibers
Lengthened contractions reduce blood flow and oxygen delivery, increasing metabolic stress through lactate accumulation and hypoxia
Mechanical tension and metabolic stress elevate intracellular calcium and IGF-1 expression, stimulating satellite cell activation and myonuclear accretion
Muscle protein synthesis exceeds breakdown, resulting in net myofiber growth specifically in the gastrocnemius
Evidence from Studies
Supporting (1)
Community contributions welcome
Triceps surae muscle hypertrophy is greater after standing versus seated calf-raise training
Contradicting (0)
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