correlational
Analysis v1
Strong Support

In certain reptiles like snakes and chameleons, both a hormone called ghrelin and the enzyme that turns it on have disappeared together over time — as if nature turned off the whole system at once.

7
Pro
0
Against

Evidence from Studies

Supporting (1)

7

Community contributions welcome

7

Ghrelin and MBOAT4 are lost in Serpentes.

Cross-Sectional Study
Animal
2026 Feb 4

Scientists found that snakes, chameleons, and toadhead agamas don’t have the hunger hormone ghrelin—and they also don’t have the special enzyme needed to turn it on. This means both parts of the system disappeared together over time, just like the claim said.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.