Eating a breakfast with 30 grams of protein reduces hunger and triggers satiety hormones equally in young adults and older adults.
Mechanism
Synthesis from 1 study
Eating 30 grams of protein at breakfast causes amino acids to reach the lower gut, where they trigger the release of fullness hormones that send signals to the brain to stop eating. This process works the same in young and older adults, with no difference in hormone levels or feeling of fullness.
Most probable mechanism
When a person eats a breakfast with 30 grams of protein, the broken-down amino acids travel to the lower intestine and trigger cells there to release hormones that signal fullness to the brain, reducing hunger and food intake, and this process works the same way in both young and older adults.
Dietary protein is digested into amino acids that reach the distal small intestine and colon.
Amino acids activate G-protein-coupled receptors on enteroendocrine L-cells in the intestinal lining.
L-cell activation triggers intracellular calcium signaling and the release of glucagon-like peptide-1 and peptide YY into the bloodstream.
Circulating glucagon-like peptide-1 and peptide YY bind to receptors on vagal afferent nerves and neurons in the hypothalamus.
Neural and hormonal signaling reduces activity in hunger centers and increases perception of fullness, suppressing appetite and reducing subsequent food intake.
Evidence from Studies
Supporting (1)
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Contradicting (0)
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