Older kidney models only worked for one specific condition, but this new model works for many different situations and matches real rat data.
Scientific Claim
Previous medullary models only considered the antidiuretic state, whereas this model regulates water and sodium excretion across various experimental conditions in agreement with rat data.
Original Statement
“In contrast to previous medullary models, which have only considered the antidiuretic state, our model is able to regulate water and sodium excretion over a variety of experimental conditions in good agreement with data from experimental studies of the rat.”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
definitive
Can make definitive causal claims
Assessment Explanation
The claim accurately reflects the abstract's comparison and data agreement statement.
Evidence from Studies
Supporting (1)
Hormonal regulation of salt and water excretion: a mathematical model of whole kidney function and pressure natriuresis.