mechanistic
Analysis v1
Strong Support
As people get older, their skin makes less of a chemical that helps blood vessels open up when it's hot, so their bodies can't cool down as well—and that makes them more likely to get sick from the heat.
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Evidence from Studies
Supporting (1)
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Community contributions welcome
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An Overview of NO Signaling Pathways in Aging
Narrative Review
2021 Jul 27This study says that as people get older, their skin makes less of a helpful chemical called nitric oxide, which helps blood vessels open up to cool the body. That means older adults have a harder time staying cool in the heat, making them more likely to get sick from it.
Contradicting (0)
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No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.