The Claim
Ambient temperature on the day of blood sampling is moderately correlated with serum IGF-1 levels (r = -0.446) and IGFBP-3 levels (r = 0.569) in healthy Korean men aged 19–40, indicating that temperature may be a key environmental driver of seasonal variation in these biomarkers.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
When it's hotter or colder outside on the day someone gives a blood sample, their body's IGF-1 and IGFBP-3 levels tend to change in predictable ways — suggesting that the weather might be one reason these health markers go up and down with the seasons.
See the scientific wording
Ambient temperature on the day of blood sampling is moderately correlated with serum IGF-1 (r = -0.446) and IGFBP-3 (r = 0.569) levels in healthy Korean men aged 19–40, suggesting temperature may be a key environmental driver of seasonal biomarker variation.
What the research says
1 studyThis study found that in young Korean men, blood levels of two important growth proteins change with the seasons—higher in some seasons, lower in others—likely because of temperature changes. So yes, the weather outside seems to affect these body markers.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.