descriptive
Analysis v1
Strong Support
After one session of knee extension exercises—whether lowering or lifting the weight—there is no measurable change in the levels of myostatin mRNA in the thigh muscle of healthy young men, when tested right after the workout.
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0
Evidence from Studies
Supporting (1)
33
Community contributions welcome
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Effect of different muscle contraction mode on the expression of Myostatin, IGF-1, and PGC-1 alpha family members in human Vastus Lateralis muscle
Randomized Controlled Trial
Human
2020 DecThe study had guys do leg exercises that either lengthen or shorten the muscle, and then checked if a gene called myostatin changed right after. It didn’t change at all, no matter what kind of exercise they did.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.