Creatine doesn’t seem to cause many problems in real life — out of millions of reports, hardly any mention it, and most of those also involve other supplements or medicines.

59

Pro

0

Against

Evidence from Studies

Supporting (1)

59

Community contributions welcome

59

Safety of creatine supplementation: analysis of the prevalence of reported side effects in clinical trials and adverse event reports

Systematic Review With Meta-Analysis

Human

2025 Sep

The study looked at millions of health reports and found that problems linked to creatine are very rare, and usually involve other supplements too—just like the claim says.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Safety of creatine supplementation: analysis of the prevalence of reported side effects in clinical trials and adverse event reports

Score: 59

DOI: 10.1080/15502783.2025.2488937

Similar Assertions

Taking creatine every day for years — even up to 14 years — doesn’t seem to cause more side effects than a fake pill, no matter your age, health, or fitness level.

59

0

74%

Taking too much creatine might be harmful, and some supplements could be contaminated with dangerous stuff like cyanide or heavy metals because of how they're made and not enough safety checks.

0

69

74%

Taking creatine — whether it's the common monohydrate type or another form — doesn't seem to cause more side effects than a fake pill, even in kids, older adults, healthy people, or those with medical conditions.

64

0

72%

Taking creatine doesn't seem to cause more stomach problems than a fake pill — the difference in upset stomachs between users and non-users is tiny and probably just due to chance.

59

0

71%