People having a heart attack have higher levels of harmful molecules called ROS/RNS in their blood compared to people with stable heart disease, which might be related to the heart attack process.
Scientific Claim
Serum levels of reactive oxygen species and reactive nitrogen species (ROS/RNS) are significantly higher in ST-elevation myocardial infarction (STEMI) patients compared to chronic coronary syndrome (CCS) patients (68.61 ± 10.23 vs. 57.26 ± 10.54; p = 0.0067), suggesting increased oxidative stress in acute coronary events.
Original Statement
“STEMI patients showed an increase in serum ROS/RNS values compared to CCS patients (STEMI vs. CCS 68.61 ± 10.23 vs. 57.26 ± 10.54; p = 0.0067) (Figure 4).”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study is observational and shows a difference between groups. The claim uses 'suggesting increased oxidative stress in acute coronary events' which appropriately reflects the observational nature of the study.