causal
Analysis v1
37
0
People with a specific version of the ACTN3 gene (the R version) tend to get much more muscle sore and weak after jumping exercises and take longer to bounce back than people with the other version (the X version), like their muscles just can’t handle the stress as well.
Context Details
Domain
exercise_science
Population
human
Subject
Individuals homozygous for the ACTN3 R577X R allele
Action
show greater voluntary force decrements and slower recovery of muscle torque
Target
after plyometric jumping exercise
Intervention Details
Type: exercise
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.
Evidence from Studies
Supporting (1)
37
37
Human alpha-actinin-3 genotype association with exercise-induced muscle damage and the repeated-bout effect.
Cross-Sectional Study
Human
2012 DecPeople with the RR gene version lost more muscle strength and took longer to recover after doing jump exercises than those with the XX version, which is exactly what the claim says.
Contradicting (0)
0
No contradicting evidence found