People with a condition called primary aldosteronism have 6% more fluid outside their cells than others, but their sodium excretion doesn't affect this fluid level.
Scientific Claim
Patients with primary aldosteronism have 6.0% higher extracellular water volume compared to normotensive and untreated hypertensive individuals, and sodium excretion is not associated with extracellular water volume in this patient group.
Original Statement
“When compared with the 510 participants, patients with primary aldosteronism had 6.0% excess in extracellular water (p = .003), and 24-h Na+ excretion was not related with extracellular water volume.”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study design allows for descriptive comparisons between groups. The claim correctly states the observed differences and lack of association without implying causation.