If you have heart disease and feel really stressed, working out regularly might help your body produce more of a brain-friendly chemical and reduce harmful inflammation in your blood.

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Evidence from Studies

Supporting (1)

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Community contributions welcome

27

Physical exercise mitigates chronic psychological stress‐induced vascular inflammation via the BDNF–Kif4–TARM1 axis

Randomized Controlled Trial

Human

2026 Apr

When stressed adults with heart disease exercise regularly, their bodies produce more BDNF, which helps calm down overactive immune cells that cause inflammation in blood vessels. This shows why exercise helps protect the heart from stress-related damage.

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Source Study

Physical exercise mitigates chronic psychological stress‐induced vascular inflammation via the BDNF–Kif4–TARM1 axis

Score: 27

DOI: 10.1002/ctm2.70674

Similar Assertions

When mice under long-term stress and with clogged arteries get to run on a wheel, their body produces a protein that calms down harmful immune cells, which helps reduce artery inflammation and keeps plaques from becoming dangerous.

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