If you're an adult with type 2 diabetes and obesity, taking diabetes drugs like semaglutide or dulaglutide might quickly shrink the fat around your heart—especially if you take a higher dose—and that could help calm down harmful inflammation nearby.

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GLP-1 receptor agonists as promising anti-inflammatory agents in heart failure with preserved ejection fraction

Narrative Review

2025 Jan

The study looked at whether drugs like semaglutide reduce inflammation in people with heart failure and obesity, and found they do—but it didn’t measure fat around the heart directly.

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Source Study

GLP-1 receptor agonists as promising anti-inflammatory agents in heart failure with preserved ejection fraction

Score: 1

DOI: 10.1007/s10741-024-10450-6

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