If you keep heating soybean oil over and over and feed it to male rats for a long time, their blood vessels start making more of a protein called LOX-1, which is linked to inflammation and artery problems — this might lead to high blood pressure.

14

Pro

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Against

Evidence from Studies

Supporting (1)

14

Community contributions welcome

14

The role of repeatedly heated soybean oil in the development of hypertension in rats: association with vascular inflammation

Cohort Study

Animal

2012 Oct

The study gave rats soybean oil that was heated ten times, and found it made a key inflammation marker (LOX-1) in their blood vessels go up — just like the claim said it would.

Contradicting (0)

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

The role of repeatedly heated soybean oil in the development of hypertension in rats: association with vascular inflammation

Score: 14

DOI: 10.1111/j.1365-2613.2012.00839.x

Similar Assertions

Heating soybean oil over and over again might cause blood vessel damage in rats, making their blood vessels more inflamed and possibly leading to high blood pressure.

14

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81%

If you feed male rats the same cooking oil over and over again after heating it multiple times, their main artery walls get thicker and stiffer, which might lead to high blood pressure.

14

0

80%